Pyridine nucleotides
Selleck Chemical LLC b-Nicotinamide Mononucleotide S5259-100mg
Nicotinamide mononucleotide ( -NM NMN) one of the key precursors of NAD and products of the NAMPT reaction is converted to NAD by nicotinamide mononucleotide adenylyltransferase
Medchemexpress LLC Nicotinic acid mononucleotide | 321-02-8 | MFCD00070358 | 98.1% | 335.2 g·mol⁻1 | C11H14NO9P | 5 MG
Nicotinic acid mononucleotide (NaMN) is a nucleotide intermediate in the biosynthesis of NAD+. It is produced from nicotinic acid via phosphoribosyltransferase and serves as a substrate for adenylyltransferases involved in NAD+ metabolism. Supplied as a research-grade reagent for biochemical and enzymatic studies.
- Intermediate in NAD+ biosynthesis and metabolism.
- Substrate for adenylyltransferase and enzymatic assays.
- High purity, typically ~98%.
- Molecular weight 335.2 g·mol⁻1; formula C11H14NO9P.
- Intended for research use only; not for human consumption.
Sigma Aldrich Fine Chemicals Biosciences beta-Nicotinamide adenine dinucleotide hydrate >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast | 53-84-9 | MFCD00036253 | 25G
beta-Nicotinamide adenine dinucleotide hydrate >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast | Purity: >=96.5% (HPLC); >=96.5% (spectrophotometric assay) | 53-84-9 | MFCD00036253 | 25G
Sigma Aldrich Fine Chemicals Biosciences β-Nicotinamide adenine dinucleotide hydrate | 53-84-9 | MFCD00036253 | 5g
β-Nicotinamide adenine dinucleotide hydrate | Purity: ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), | MW:663.43 (anhydrous basis) | 53-84-9 | MFCD00036253 | 5g
Sigma Aldrich Fine Chemicals Biosciences beta-Nicotinamide adenine dinucleotide hydrate >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast | 53-84-9 | MFCD00036253 | 250MG
beta-Nicotinamide adenine dinucleotide hydrate >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast | Purity: >=96.5% (HPLC); >=96.5% (spectrophotometric assay) | 53-84-9 | MFCD00036253 | 250MG
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine5G
adenine beta Nicotinamide adenine5G
Cayman Chemical 6-Mercaptopurine Riboside, Purity: ≥98%, CAS: 574-25-4, 100 mg
A derivative of 6-mercaptopurine; active against S. faecalis when used at 0.05 to 15 mg/ml; inhibits autophagy and cholesterol synthesis in isolated and washed rat hepatocytes at 0.5, 1, or 1.5 mM; decreases tumor growth in mice bearing 6-mercaptopurine susceptible adenocarcinoma 755 tumors at 17, 35, or 70 mg/kg per day
Apexbio Technology LLC Nicotinamide(Synonyms: Nicotinic acid amide, Vitamin B3 amide, Niacinamide, Pyridine-3-carboxamide, 3-Pyridinecarboxamide), 1g, CAS: 98-92-0.
Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
Apexbio Technology LLC Nicotinamide(Synonyms: Nicotinic acid amide, Vitamin B3 amide, Niacinamide, Pyridine-3-carboxamide, 3-Pyridinecarboxamide), 10mM (in 1mL DMSO), CAS: 98-92-0.
Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
Apexbio Technology LLC NAD+ 53-84-9 10mM (in 1mL H2O)
Nicotinamide adenine dinucleotide (NAD CAS number 53-84-9) is a coenzyme involved in oxidation-reduction reactions accepting electrons to form NADH Additionally NAD functions as a substrate in enzymatic processes mediated by poly(ADP-ribose) polymerases sirtuins and cyclic ADP-ribose synthases NAD analogs demonstrate inhibitory activity against CD38-associated NAD glycohydrolase (NADase) with reported IC50 values ranging from 2 mM to 10 mM In biomedical research NAD supplementation is investigated for addressing fatigue and fatigue-associated disorders
eMolecules 98-92-0 | Nicotinamide | Oakwood Chemicals | MFCD00006395 | 122.127 | C6H6N2O | 99.000 | NC(=O)c1cccnc1 | 1kg | 480163728
Nicotinamide | Oakwood Chemicals | 98-92-0 | MFCD00006395 | 122.127 | C6H6N2O | 99.000 | NC(=O)c1cccnc1 | 1kg | 480163728
Medchemexpress LLC Nicotinamide riboside malate | 2415659-01-5 | MFCD34549739 | 98.0% | 388.33 g/mol | C15H20N2O10 | 1G
Nicotinamide riboside malate is the malate salt form of nicotinamide riboside, a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+) used in research to elevate intracellular NAD+ levels and probe sirtuin-mediated pathways. It is commonly employed in studies of metabolism, aging, and mitochondrial function and is provided as a solid reagent for laboratory research (CAS 2415659-01-5).
- Orally bioavailable NAD+ precursor.
- Supports increased intracellular NAD+ levels.
- Enables sirtuin activation and metabolic pathway studies.
- Suitable for research on aging and mitochondrial function.
- Supplied as a solid powder for laboratory use.
Medchemexpress LLC Adenosine, N-(2-furanylmethyl)- | 4338-47-0 | MFCD00037987 | 99.9% | 347.33 g/mol | C15H17N5O5 | 50 MG
Kinetin riboside (Adenosine, N-(2-furanylmethyl)-) is a ribosylated cytokinin analog used in biochemical and cell biology research. It induces apoptosis in cancer cells and inhibits proliferation of HCT-15 cells (IC50 = 2.5 μM). The reagent is supplied as a high-purity solid and is intended for cell-based assays investigating apoptosis, proliferation, and cytotoxicity.
- High purity: 99.88%.
- Molecular weight: 347.33 g/mol.
- Chemical formula: C15H17N5O5.
- Appearance: solid, white to off-white.
- Storage: powder -20°C for long term; in solvent -80°C recommended.
- Reported bioactivity: induces apoptosis and inhibits HCT-15 cell proliferation (IC50 2.5 μM).
- Pack sizes suitable for small-scale research, including 50 mg.